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Harnessing the Power of Systems Immunology for Sepsis Diagnosis and Treatment: Opportunities and Challenges

Sepsis, an abnormal, life-threatening reaction to infection often leading to organ dysfunction and failure, represents a significant yet often under-recognized global health issue. Despite accounting for nearly 20% of all deaths worldwide, its complex and heterogeneous nature often leads to misdiagnosis and mistreatment. With the advent of the COVID-19 pandemic, the imperative for effectual sepsis…

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Navigating the Severe National Shortage of Essential Blood Culture Bottles: Risks, Mitigations, and Solutions

Across America, hospitals have been grappling with an acute shortage of blood culture bottles, pivotal in diagnosing serious, potentially fatal bloodstream infections. The Centers for Disease Control and Prevention issued a warning to health care professionals, lab specialists, health facility administrators, and state, tribal, and local health bodies, cautioning the shortage of Bactec blood culture…

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