Catheter-related bloodstream infection (CRBSI), a severe type of hospital-acquired infection, is commonly associated with the use of central venous catheters (CVCs). With growing concerns around antibiotic resistance and multidrug-resistant organisms (MDROs), the correlation between MDROs and CRBSI is gaining heightened scrutiny. Moreover, given the scarcity of literature on CRBSI in relation to MDROs, this comprehensive retrospective study aims to underpin this association and illuminate targeted interventions.
The study period, spanning between January 2019 and June 2023, saw the inclusion of 50,718 hospitalized patients with implanted CVCs. In that timeframe, 122 cases of CRBSI occurred. After adjusting for other factors such as age, gender, medical history, environmental, and catheter-related factors, a strong correlation was found between MDROs and an increased incidence of CRBSI. The findings of this study underscore the importance of devising targeted infection control strategies against MDRO-associated CRBSI.
Collaborative efforts across disciplines can further enhance the management of such infections and improve patient outcomes. Alongside the incidence of CRBSI, potential influences on their occurrence like patient conditions, types of catheters used, and hospital departments were investigated. The study reveals essential insights into how MDROs, plus these factors, contribute towards the incidence of CRBSI.
The study results and analyses are beneficial not only for healthcare professionals attending to patients with catheters but also for administrators and policymakers dedicated to improving healthcare results while mitigating costs related to hospital-acquired infections and antibiotic resistance.
Source: https://bmcinfectdis.biomedcentral.com/articles/10.1186/s12879-025-11367-7