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Exploring Multi-Drug Resistant Bacteria on Hospital Surfaces and the Challenge of HPV Vaccination in Adults

Recent research published in Nature Communications analyzes the prevalence of multidrug-resistant bacteria colonizing hospital surfaces in six low- to middle-income countries (LMICs). This research, led by Cardiff University, collected a total of 6,290 hospital surface swabs from 10 hospitals in Bangladesh, Ethiopia, Nigeria, Pakistan, Rwanda, and South Africa. The aim was to identify the diversity and prevalence of Extended-Spectrum Beta-Lactamase (ESBL) and carbapenemase-carrying bacterial species present in neonatal wards.

The findings showed that 60.7% of the collected swabs were positive for gram-negative bacteria, while 13.3% were confirmed to carry ESBL and carbapenemase genes. This bacteria prevalence was particularly noticed around sink drains, medical equipment, and ward furniture. In addition to this, further testing of the isolates using MALDI-TOF mass spectrometry established Klebsiella pneumoniae as the most frequently found carbapenemase-producing bacteria.

The implication of these bacteria on neonatal sepsis was also explored in the BARNARDS study where bacteria from infected neonatal blood and hospital surfaces showed striking similarities in their genetic sequence. The research further emphasizes the importance of maintaining stringent infection prevention practices in hospitals, especially in countries with limited resources.

In another development, a recent survey study published in Human Vaccines & Immunotherapeutics expressed concerns over the low uptake of the Human Papillomavirus (HPV) vaccine among US adults aged between 27 to 45 years, particularly among men, Hispanic respondents, and people with lesser education. In 2018, the Food and Drug Administration (FDA) expanded the vaccination age limit, extending it to 45 years, which upped the need to study HPV vaccine uptake among this diverse population.

Data analysis from the 2019 National Health Interview Survey revealed that 84.5% of the participant, totalling over 9,000, have yet to be vaccinated. This glaring lack has raised concerns over cancer prevention efforts and emphasized the need to address and mitigate these disparities. Therefore, development, implementation and promotion of effective strategies to increase vaccination rates not only safeguards individual health, but is also crucial in broader disease prevention.

Source: https://www.cidrap.umn.edu/antimicrobial-stewardship/study-finds-widespread-bacterial-contamination-hospital-surfaces-low-and

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